(R)-tert-Butyl (1-(3-bromophenyl)-2-hydroxyethyl)carbamate - Names and Identifiers
Name | Carbamic acid, [(1R)-1-(3-bromophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester
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Synonyms | tert-Butyl (R)-(1-(3-bromophenyl)-2-hydroxyethyl)carbamate (R)-tert-Butyl (1-(3-bromophenyl)-2-hydroxyethyl)carbamate Carbamic acid, [(1R)-1-(3-bromophenyl)-2-hydroxyethyl]-, 1,1... Carbamic acid, [(1R)-1-(3-bromophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester Carbamic acid, [(1R)-1-(3-bromophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester (9CI)
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CAS | 380610-92-4
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(R)-tert-Butyl (1-(3-bromophenyl)-2-hydroxyethyl)carbamate - Physico-chemical Properties
Molecular Formula | C13H18BrNO3
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Molar Mass | 316.19 |
Storage Condition | Sealed in dry,Room Temperature |
(R)-tert-Butyl (1-(3-bromophenyl)-2-hydroxyethyl)carbamate - Introduction
Carbamic acid, [(1R)-1-(3-bromophene)-2-hydroxyethyl]-, 1,1-dimethyleyl ester is an organic compound with the chemical formula C12H17BrNO3. It is a white or off-white crystalline solid that is stable at room temperature.
Nature:
Carbamic acid, [(1R)-1-(3-bromophene)-2-hydroxyethyl]-, 1,1-dimethylester is a chiral compound with one chiral center. It is an aminated alcohol compound containing a Boc protecting group (tert-butoxycarbonyl) and an amino group. The thermal stability of the compound is high.
Use:
Carbamic acid, [(1R)-1-(3-bromophene)-2-hydroxyethyl]-, 1,1-dimethylester is commonly used in chiral synthesis in organic synthesis. It can be used as a chiral intermediate for the preparation of chiral drugs and bioactive molecules. It can also be used in the synthesis of catalysts and chelating agents for organic synthesis reactions.
Preparation Method:
The preparation method of Carbamic acid, [(1R)-1-(3-bromophenyl)-2-hydroxyethyl]-, 1,1-dimethylethyl ester can use various routes. One common method is by first preparing (R)-B-(Boc-amino)-3-bromobenzeneacetaldehyde, which is then reacted with sodium hydroxide and N,N-dimethylformamide to give the desired product.
Safety Information:
Carbamic acid, [(1R)-1-(3-bromophene)-2-hydroxyethyl]-, 1,1-dimethylester has good safety, but as a chemical, it is still necessary to strictly abide by the operating procedures and safety measures. During use, care should be taken to avoid contact with skin and eyes, and to avoid inhaling its dust or vapor. Wear appropriate personal protective equipment such as lab gloves, goggles and protective masks when handling the compound.
In addition, laboratories where the compound is synthesized and used should have appropriate ventilation and safety equipment, and should be handled and stored in accordance with relevant regulations.
Last Update:2024-04-09 20:52:54